P.R.A.M. method
MostCare® implements the innovative Pressure Recording Analytical Method P.R.A.M.
Different from the other methods also based on the analysis of the arterial pressure signal (PCM, Pulse Contour Methods) the evaluation of Cardiac Output by PRAM requires neither calibration procedures, nor anthropometric data (height, weight, age and gender) to refer to experimental in-vitro measurements.
PRAM is just based on the objective analysis of the whole arterial pressure wave morphology (both systole and diastole) at every heartbeat, with sampling rate of 1000Hz and automatic detection of all significant curve points: systolic and diastolic points, dicrotic notch and points of instability.
These points and the wave contour are evaluated and weighted according to the application of the physical theory of perturbations, in order to obtain the systemic impedance and the haemodynamic parameters.
PRAM methodology, independent on any calibration or reference data, can be applied to any patient without limitations, in both stable and instable conditions. Critical patients, septic patients, paediatric patients and patients with contrapulsator or other external mechanical support can be monitored with MostCare.
The objective analysis of the pressure waveform provides additional parameters for the determination of fluid responsiveness (SVV, PPV, SPV and DPV) and cardiac functionality (dP/dt, CCE).
